Facebook Yep, it's a no-brainer, and yep, it's sometimes sluggish, but the official app is still the best way to keep up on Facebook.
TweetCaster Pro for Twitter A really nice Twitter client that is reliable and updated regularly. Particularly useful on tablets with the extra screen real-estate.
Path Path is pretty new but growing in popularity. It's almost like a neat journal of the minutiae of your life.
Twitter The official Twitter app keeps improving. Sometimes it's still the most reliable because it updates very quickly.
Google+ It's not dead! It might not be as popular as the other players out there, but it's still good to check now and again and this app is super nice looking.
LinkedIn When you wanna get all professional, LinkedIn is the place to be. It's important to be on here if you're job hunting these days.